RNA Details
Disease Name
keloid
Tissue
skin
RNA Symbol
mir-203a
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
homo sapiens
Detection Methods
qRT-PCR; dual-lucimmunofluorescenceerase reporter assay etc.
Target
EGR1; FGF2
Pathway
NA
PubMed ID
Title
"MiR-203 regulates keloid fibroblast proliferation, invasion, and extracellular matrix expression by targeting EGR1 and FGF2"
Year
2018
Function
"We demonstrated for the first time that mir-203 decreased the proliferation, invasion, and ecm production of keloid fibroblasts by repressing egr1 and fgf2 expression, suggesting a potential role of mir-203 in preventing and treating keloids."